Estimation of sperm DNA fragmentation index in ICSI cycles: does it affect the outcome?
نویسندگان
چکیده
منابع مشابه
Effects of Sperm DNA Fragmentation on Semen Parameters and ICSI Outcome Determined by an Improved SCD Test, Halosperm
Background Sperm DNA fragmentation is known as an important cause of male infertility. The influence of sperm DNA damage on reproductive potential has been subject of many studies indicating various results and remaining the subject controversial. In this study, we investigated differences of the semen parameters and intracytoplasmic sperm injection (ICSI) outcome according to sperm DNA fragmen...
متن کاملDoes the presence of nuclear vacuoles in human sperm selected for ICSI affect pregnancy outcome?
BACKGROUND To verify whether or not microinjection of sperm with a normal nuclear shape but large vacuoles affects IVF-ICSI pregnancy outcome. METHODS A comparative study testing IVF outcome parameters of IVF-ICSI, based on morphological selection of spermatozoa with normal nuclei against those based on microinjection of sperm with a normal nuclear shape but large vacuoles. An experimental gr...
متن کاملICSI significantly improved the pregnancy rate of patients with a high sperm DNA fragmentation index
OBJECTIVE Correlations between semen parameters and sperm DNA fragmentation index (DFI) were investigated to identify characteristics of sperm without DNA damage that could be used in selecting sperm for intracytoplasmic sperm injection (ICSI). Pregnancy outcomes were compared to determine whether in vitro fertilization (IVF) or ICSI is a better choice for patients who have sperm with a high-DF...
متن کاملThe Effect of Body Mass Index on the Outcome of IVF/ICSI Cycles in Non Polycystic Ovary Syndrome Women
Background The aim of this study was to investigate the effect of body mass index (BMI) on the outcome of in vitro fertilization (IVF)/ intracytoplasmic sperm injection (ICSI) cycles in non polycystic ovary syndrome (PCOs) women. MaterialsAndMethods In this cross sectional study, 287 infertile non PCOs women referred to Royan institute, Tehran, Iran between 2002 and 2003 were enrolled. Patients...
متن کاملP-240: Effect of Oxidative Stress on DNA Fragmentation Index in Sperm of Mature Mice
Background: One of the major factors affecting on male infertility is oxidative stress (OS). Two main sources of ROS production are leukocytes and spermatozoa. The ROS such as tertiary-butyl hydroperoxide (TBHP) may damage and fragmentate to sperm DNA, which can lead to complications in the offspring. In this study, we will investigate the effect of od on DNA fragmentation index (DFI) in sperm ...
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ژورنال
عنوان ژورنال: Fertility and Sterility
سال: 2018
ISSN: 0015-0282
DOI: 10.1016/j.fertnstert.2018.07.821